It’s darn delightful science! Cannabidiol (CBD) seems to speed the healing of broken bones. Studies also suggest that CBD helps build stronger bonds; it can leave your bones better fortified.
Read on for studies of broken bones and CBD.
Biochemical Pharmacology. 2014 February 1. “Increase of mesenchymal stem cell migration by cannabidiol via activation of p42/44 MAPK.”
This study from Germany was done with test tubes, not people… but it suggests that CBD may activate CB2 receptors to send more stem cells to broken bones.
Journal of Bone and Mineral Research. 2015 May. “Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts.”
This study of CBD and bone healing comes from Dr. Raphael Mechoulam, the first scientist to discover delta-9-THC, and 17 colleagues from Israel, Sweden and Switzerland.
The team concludes that CBD enhanced the healing of rats’ broken legs. CBD stimulated production of lysyl hydroxylase, an enzyme known to promote bone healing.
Proceedings of the National Academy of Sciences. 2009 September 22. “The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.”
Many scientists have reported that CBD activates CB2 receptors. This study is the first to say that CBD also acts on the endocannabinoid receptor GPR55.
Working with GPR55, CBD may help regulate bone mass by inhibiting the growth of osteoclasts. Left alone, osteoclasts would absorb more bone-building minerals.